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CAFFEINE
Get complete, unbiased, scientific information on CAFFEINE, including Safety Ratings,
Effectiveness Ratings, Interaction Ratings, Lists of Ingredients and Adverse
Reactions... all from Natural Medicines Comprehensive Database
 
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Full MonographInteractions with DrugsAlso Known As
SafetyInteractions with HerbsPeople Use This For
EffectivenessInteractions with FoodEditor's Comments
Adverse ReactionsInteractions with Lab TestsReferences
Dosage/AdministrationInteractions with DiseasesPatient Handout
Mechanism of Action
 
 Natural Medicines Comprehensive DatabaseView 604 Products Containing: CAFFEINE
View 32 Canadian Licensed Products Containing: CAFFEINE
 
 Also Known As: return to top
Anhydrous Caffeine, Caffeine and Sodium Benzoate, Caffeine Anhydrous, Caffeine Citrate, Citrated Caffeine, Methylxanthine, Trimethylxanthine.
CAUTION: See separate listings for Black Tea, Green Tea, Oolong Tea, Coffee, Cola Nut, Guarana, and Mate.
 Scientific Name: return to top
1,3,7-trimethylxanthine.
 People Use This For: return to top
Natural medicines are often tried for many conditions based on tradition, anecdotes, or
marketing, but not all of these uses are supported by reliable or credible scientific
research. Below is a list of some common uses for CAFFEINE.
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Orally, caffeine is used in combination with analgesics and ergotamine for treating migraine headaches. It is used orally with analgesics for simple headaches and preventing and treating postoperative and postdural puncture headaches. It is also used orally for asthma, gallbladder disease, attention-deficit hyperactivity disorder (ADHD), neonatal apnea, hypotension, increasing mental alertness, and enhancing athletic performance. Caffeine is used for weight loss and type 2 diabetes. Very high doses are used as euphoriants, often in combination with ephedrine as an alternative to illicit stimulants.
Topically, caffeine cream preparations have been used for reducing erythema and itching in dermatitis.
Rectally, caffeine is used in combination with ergotamine for migraine headaches.
Parenterally, caffeine is used for postoperative and postdural puncture headache, neonatal apnea, acute respiratory depression, and as a diuretic. It is also used for extending the length of seizure with electroconvulsive therapy.
In foods, caffeine is used as an ingredient in soft drinks, energy drinks, and other beverages.

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 Safety: return to top
Get reliable information about potential safety concerns from scientific Safety Rating. See if there are warnings against use during Pregnancy, Breast Feeding, or for Children.
 Effectiveness: return to top
Get scientific Effectiveness Rating and see if CAFFEINE works before selecting it.
 Mechanism of Action: return to top
Research the pharmacology, active constituents, and a clear scientific explanation about how the natural medicine is thought to work for its medicinal uses.
 Adverse Reactions: return to top
Get detailed information on common side effects and potentially serious adverse reaction. Find out what to expect if you select this natural product.
 Interactions with Herbs & Supplements: return to top
Find out if CAFFEINE is safe to take with other natural medicines or supplements or if there are potential interactions.
 Interactions with Drugs: return to top
Find out what medications CAFFEINE interacts with and if the interactions are mild or potentially dangerous.
 Interactions with Foods: return to top
Find out if particular foods should be avoided with CAFFEINE, Ginkgo, or if certain foods can negatively affect the product.
 Interactions with Lab Tests: return to top
Find out if CAFFEINE interferes with laboratory tests or could cause a diagnostic test to fail or be inaccurate.
 Interactions with Diseases or Conditions: return to top
Find out if CAFFEINE interferes with or could worsen any medical condition or if there are any precautions or contraindications.
 Dosage/Administration: return to top
Get reliable information on the best dose to use based on scientific research. Products only work if taken in the correct dose. Taking a dose that is too high can increase the chance of side effects and adverse outcomes.
 Editor's Comments: return to top
Get comments from the editors about special concerns, interesting facts, and other information.


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