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MELATONIN
Get complete, unbiased, scientific information on MELATONIN, including Safety Ratings,
Effectiveness Ratings, Interaction Ratings, Lists of Ingredients and Adverse
Reactions... all from Natural Medicines Comprehensive Database
 
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Full MonographInteractions with DrugsAlso Known As
SafetyInteractions with HerbsPeople Use This For
EffectivenessInteractions with FoodEditor's Comments
Adverse ReactionsInteractions with Lab TestsReferences
Dosage/AdministrationInteractions with DiseasesPatient Handout
Mechanism of Action
 
 Natural Medicines Comprehensive DatabaseView 386 Products Containing: MELATONIN
View 115 Canadian Licensed Products Containing: MELATONIN
 
 Also Known As: return to top
MEL, MLT, Pineal Hormone.
CAUTION: See separate listing for Melanotan-II.
 Scientific Name: return to top
N-acetyl-5-methoxytryptamine.
 People Use This For: return to top
Natural medicines are often tried for many conditions based on tradition, anecdotes, or
marketing, but not all of these uses are supported by reliable or credible scientific
research. Below is a list of some common uses for MELATONIN.
Subscribe now to get scientific Effectiveness Ratings for MELATONIN and thousands
of other natural medicines. Get the facts before your take it.

Orally, melatonin is used for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind, and benzodiazepine and nicotine withdrawal. Melatonin is also used orally for Alzheimer's disease, tinnitus, depression, delayed sleep phase syndrome (DSPS), chronic fatigue syndrome (CFS), fibromyalgia, migraine and cluster headaches, idiopathic stabbing headache, and insomnia associated with attention deficit-hyperactivity disorder (ADHD), and irritable bowel syndrome (IBS). Other uses include hypertension, hyperpigmentation, osteoporosis, breast cancer, brain cancer, lung cancer, prostate cancer, head cancer, neck cancer, and gastrointestinal cancer. It is also used for thrombocytopenia, cachexia, neuropathy, and asthenia associated with cancer chemotherapy. Melatonin is also used orally for epilepsy, as an antiaging agent, for menopause, as preanesthetic medication, and for birth control.
Transbuccal and sublingual forms of melatonin are also used for insomnia, shift-work disorder, and as preanesthetic medication.
Topically, melatonin is used as a skin protectant against ultraviolet (UV) light and sunburn.
Intramuscularly, melatonin is used for treating cancer.

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 Safety: return to top
Get reliable information about potential safety concerns from scientific Safety Rating. See if there are warnings against use during Pregnancy, Breast Feeding, or for Children.
 Effectiveness: return to top
Get scientific Effectiveness Rating and see if MELATONIN works before selecting it.
 Mechanism of Action: return to top
Research the pharmacology, active constituents, and a clear scientific explanation about how the natural medicine is thought to work for its medicinal uses.
 Adverse Reactions: return to top
Get detailed information on common side effects and potentially serious adverse reaction. Find out what to expect if you select this natural product.
 Interactions with Herbs & Supplements: return to top
Find out if MELATONIN is safe to take with other natural medicines or supplements or if there are potential interactions.
 Interactions with Drugs: return to top
Find out what medications MELATONIN interacts with and if the interactions are mild or potentially dangerous.
 Interactions with Foods: return to top
Find out if particular foods should be avoided with MELATONIN, Ginkgo, or if certain foods can negatively affect the product.
 Interactions with Lab Tests: return to top
Find out if MELATONIN interferes with laboratory tests or could cause a diagnostic test to fail or be inaccurate.
 Interactions with Diseases or Conditions: return to top
Find out if MELATONIN interferes with or could worsen any medical condition or if there are any precautions or contraindications.
 Dosage/Administration: return to top
Get reliable information on the best dose to use based on scientific research. Products only work if taken in the correct dose. Taking a dose that is too high can increase the chance of side effects and adverse outcomes.
 Editor's Comments: return to top
Get comments from the editors about special concerns, interesting facts, and other information.


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