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ST. JOHN'S WORT
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Full MonographInteractions with DrugsAlso Known As
SafetyInteractions with HerbsPeople Use This For
EffectivenessInteractions with FoodEditor's Comments
Adverse ReactionsInteractions with Lab TestsReferences
Dosage/AdministrationInteractions with DiseasesPatient Handout
Mechanism of Action
 
 Natural Medicines Comprehensive DatabaseView 758 Products Containing: ST. JOHN'S WORT
View 161 Canadian Licensed Products Containing: ST. JOHN'S WORT
 
 Also Known As: return to top
Amber, Amber Touch-and-Heal, Demon Chaser, Fuga Daemonum, Goatweed, Hardhay, Hypereikon, Hyperici Herba, Hypericum, Klamath Weed, Millepertuis, Rosin Rose, Saynt Johannes Wort, SJW, Tipton Weed.
 Scientific Name: return to top
Hypericum perforatum.
Family: Hypericaceae or Clusiaceae.
 People Use This For: return to top
Natural medicines are often tried for many conditions based on tradition, anecdotes, or
marketing, but not all of these uses are supported by reliable or credible scientific
research. Below is a list of some common uses for ST. JOHN'S WORT.
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Orally, St. John's wort is used for depression, dysthymia, anxiety, heart palpitations, mood disturbances associated with menopause, attention deficit-hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), and seasonal affective disorder (SAD). Other uses include exhaustion, smoking cessation, fibromyalgia, chronic fatigue syndrome (CFS), menopausal symptoms, fibrositis, headache, migraine headache, muscle pain, neuralgia, and sciatica. It is also used orally for secondary symptoms associated with depression such as fatigue, loss of appetite, insomnia, and anxiety. It is also used orally for cancer, vitiligo, HIV/AIDS, hepatitis C, weight loss, and as a diuretic. Oily St. John's wort preparations are used orally for gastric indigestion.
Topically, oily St. John's wort preparations are used for treating bruises and abrasions, inflammation and muscle pain, first degree burns, wound healing, bug bites, hemorrhoids, vitiligo, and neuralgia.
In manufacturing, the hypericin-free extracts of St. John's wort are used in the making of alcoholic beverages.

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 Safety: return to top
Get reliable information about potential safety concerns from scientific Safety Rating. See if there are warnings against use during Pregnancy, Breast Feeding, or for Children.
 Effectiveness: return to top
Get scientific Effectiveness Rating and see if ST. JOHN'S WORT works before selecting it.
 Mechanism of Action: return to top
Research the pharmacology, active constituents, and a clear scientific explanation about how the natural medicine is thought to work for its medicinal uses.
 Adverse Reactions: return to top
Get detailed information on common side effects and potentially serious adverse reaction. Find out what to expect if you select this natural product.
 Interactions with Herbs & Supplements: return to top
Find out if ST. JOHN'S WORT is safe to take with other natural medicines or supplements or if there are potential interactions.
 Interactions with Drugs: return to top
Find out what medications ST. JOHN'S WORT interacts with and if the interactions are mild or potentially dangerous.
 Interactions with Foods: return to top
Find out if particular foods should be avoided with ST. JOHN'S WORT, Ginkgo, or if certain foods can negatively affect the product.
 Interactions with Lab Tests: return to top
Find out if ST. JOHN'S WORT interferes with laboratory tests or could cause a diagnostic test to fail or be inaccurate.
 Interactions with Diseases or Conditions: return to top
Find out if ST. JOHN'S WORT interferes with or could worsen any medical condition or if there are any precautions or contraindications.
 Dosage/Administration: return to top
Get reliable information on the best dose to use based on scientific research. Products only work if taken in the correct dose. Taking a dose that is too high can increase the chance of side effects and adverse outcomes.
 Editor's Comments: return to top
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