increased use of spironolactone for heart failure is causing more hospitalizations and deaths

The increased use of spironolactone for heart failure is causing more hospitalizations and deaths.

The problem started a few years ago when the "Randomized Aldactone Evaluation Study" (RALES) showed improved outcomes in patients with severe heart failure.

Since that study was published, lots of heart failure patients were put on spironolactone.

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