Avoid Even One Dose of Fluconazole in Pregnant Women
June 2016
New warnings will raise concerns about a possible increased risk of miscarriage with ONE dose of fluconazole (Diflucan, etc).
Vaginal azoles (clotrimazole, etc) are first-line for vaginal candidiasis in pregnancy. But the hassle of using a vaginal product for a week may lead to requests for oral fluconazole instead.
Current labeling warns about birth defects with LONG-term use of HIGH-dose fluconazole... 400 to 800 mg/day.
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