Know Which Patients Are Prone to Faster Renal Clearance

November 2018

You'll hear buzz about antibiotic dosing in patients with "augmented renal clearance" (ARC)...or higher clearance than normal.

Up to two-thirds of general ICU patients may have ARC...a creatinine clearance above 130 mL/min...usually during their first week in the ICU.

The concern is that ARC may lead to inadequate antibiotic blood levels...due to faster clearance of meds.

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