Explain How New Rx Tradipitant Stacks Up for Motion Sickness
June 2026
Questions about how to prevent motion sickness are spinning due to new tradipitant (Nereus)...the first Rx option approved in over 40 years.
It blocks neurokinin-1 (NK-1) receptors...to reduce the binding of substance P, a neurotransmitter involved in motion-induced vomiting.
Taking tradipitant 85 or 170 mg po about 60 minutes before a triggering event (boat trip, etc) prevents VOMITING in about 1 in 4 adults with a history of motion sickness versus placebo...with minimal sedation.
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